CFP anticorps
Aperçu rapide pour CFP anticorps (ABIN181117)
Antigène
Voir toutes CFP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises human factor P, a 53 kDa glycosylated protein present in blood serum.
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Attributs du produit
- Synonyms: CFP, PFC, Complement factor P
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Purification
- Affinity chromatography on Protein A
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Immunogène
- Native purified factor P from human serum.
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Isotype
- IgG1
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Indications d'application
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ELISA. Functional Assays. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Borate buffered saline pH 8.2 containing 0.02 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- CFP (Complement Factor P (CFP))
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Autre désignation
- Properdin
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Sujet
- Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Synonyms: CFP, Complement factor P, PFC
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ID gène
- 5199
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UniProt
- P27918
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Pathways
- Système du Complément
Antigène
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