CFP anticorps

N° du produit ABIN181117

Détail du produit anti-CFP anticorps

Antigène: CFP (Complement Factor P (CFP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CFP est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Specificité: This antibody recognises human factor P, a 53 kDa glycosylated protein present in blood serum.

Attributs du produit: Synonyms: CFP, PFC, Complement factor P

Purification: Affinity chromatography on Protein A

Immunogène: Native purified factor P from human serum.

Clone: 01-10-18

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Functional Assays. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Borate buffered saline pH 8.2 containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CFP

Antigène: CFP (Complement Factor P (CFP))

Autre désignation: Properdin (CFP Produits)

Synonymes: anticorps BFD, anticorps PFC, anticorps PFD, anticorps PROPERDIN, anticorps BCFG, anticorps Pfc, anticorps Properdin, anticorps complement factor properdin, anticorps CFP, anticorps Cfp

Sujet: Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Synonyms: CFP, Complement factor P, PFC

ID gène: 5199

UniProt: P27918

Pathways: Système du Complément