EPH Receptor A4 anticorps (C-Term)

N° du produit ABIN181176

Cet anticorps anti-EPH Receptor A4 Polyclonal Lapin (ABIN181176) détecte spécifiquement EPH Receptor A4 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EPH Receptor A4 anticorps (C-Term) (ABIN181176)

Antigène: EPH Receptor A4 (EPHA4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-EPH Receptor A4 anticorps

Épitope: C-Term

Specificité: This antibody detects Ephrin Type A Receptor 4.

Purification: Immunoaffinity chromatography

Immunogène: EPHA4 antibody was raised against synthetic peptide from C-terminal domain of human EPHA4. Genename: EPHA4

Information d'application

Indications d'application: Immunohistochemistry: 18 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS containing 0.009 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur EPH Receptor A4

Antigène: EPH Receptor A4 (EPHA4)

Autre désignation: EPHA4

Sujet: Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: Ephrin type-A receptor 4, HEK8, Receptor protein-tyrosine kinase HEK8, SEK, TYRO1, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK

ID gène: 2043

NCBI Accession: NP_004429

UniProt: P54764

Pathways: Signalisation RTK