APOE anticorps (Isoform E3)
-
- Antigène Voir toutes APOE Anticorps
- APOE (Apolipoprotein E (APOE))
-
Épitope
- Isoform E3
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp APOE est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects ApoE3. Cross reacts with ApoE2 and ApoE4.
- Purification
- Immunoaffinity chromatography
- Immunogène
- Highly pure (> 98 %) recombinant human ApoE3
- Top Product
- Discover our top product APOE Anticorps primaire
-
-
- Indications d'application
-
ELISA: Indirect: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hApoE3. Sandwich: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with Biotinylated Anti-HumanApoE3 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hApoE3. Western blot: To detect hApoE3 this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hApoE3 is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Reconstitution
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- PBS, pH 7.2
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
- Date de péremption
- 6 months
-
- Antigène
- APOE (Apolipoprotein E (APOE))
- Autre désignation
- Apolipoprotein E (Apo E) (APOE Produits)
- Synonymes
- anticorps ad2, anticorps apoprotein, anticorps im:7036787, anticorps wu:fb69a05, anticorps zgc:110064, anticorps apoe, anticorps AI255918, anticorps AD2, anticorps LDLCQ5, anticorps LPG, anticorps APOEA, anticorps Apo-E, anticorps apolipoprotein E, anticorps apolipoprotein Ea, anticorps apoe, anticorps apoea, anticorps Apoe, anticorps APOE
- Sujet
- Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
- ID gène
- 348
- NCBI Accession
- NP_000032
- UniProt
- P02649
- Pathways
- Regulation of Cell Size, Lipid Metabolism
-