Galectin 3 anticorps (Biotin)

N° du produit ABIN181681

Cet anticorps Lapin Polyclonal détecte spécifiquement Galectin 3 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Galectin 3 anticorps (Biotin) (ABIN181681)

Antigène: Galectin 3 (LGALS3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Galectin 3 est conjugé à/à la Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Galectin 3 anticorps (Biotin)

Purification: Affinity Chromatography.

Immunogène: Highly pure (> 98%) recombinant human Galectin-3

Information d'application

Indications d'application: ELISADirect: To detect hGalectin-3 (using 100 μL/well antibody solution) a concentration ofapprox. 1.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, allows the detection of at least 0.2-0.4 ng/well of recombinant HumanGalectin-3. Sandwich: To detect Human Galectin-3 (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. In conjunction with PolyclonalAnti-Human Galectin-3 (ABIN181683 or ABIN181684) as a capture antibody, it allows thedetection of at least 0.2-0.4 ng/well of recombinant Human Galectin-3. Western blot

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Date de péremption: 6 months

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: Galectin-3

Classe de substances: Chemical

Sujet: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2

ID gène: 9606

UniProt: P17931

Pathways: Signalisation RTK