L’anticorps Rat Monoclonal anti-Macrophage Scavenger Receptor 1 a été validé pour FACS. Il convient pour détecter Macrophage Scavenger Receptor 1 dans des échantillons de Souris.
N° du produit ABIN181781
Aperçu rapide pour Macrophage Scavenger Receptor 1 anticorps (PE) (ABIN181781)
This antibody recognises the murine scavenger receptor class A (SRA), type I and II, also known as CD204. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recent research shows that clone 2F8 recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
Purification
Affinity chromatography on Protein G
Immunogène
RAW264 cell line. Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.
Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with 1 mL distilled water.
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène
Macrophage Scavenger Receptor 1 (MSR1)
Autre désignation
CD204
Sujet
CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.Synonyms: MSR1, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, Scavenger receptor class A member 1