CD68 anticorps (PE)
Aperçu rapide pour CD68 anticorps (PE) (ABIN181838)
Antigène
Voir toutes CD68 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody recognizes CD68. SM1550R does detect surface Macrosialin at low levels in resident Mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
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Purification
- Affinity Chromatography on Protein G
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Isotype
- IgG2a
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Indications d'application
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Flow cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL. Membrane permeabilisation is required for this application. ABIN181838 does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 1.0 mL distilled water.
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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: "SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages." dans: The American journal of pathology, Vol. 175, Issue 3, pp. 1107-15, (2009) (PubMed).
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: "SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages." dans: The American journal of pathology, Vol. 175, Issue 3, pp. 1107-15, (2009) (PubMed).
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- CD68 (CD68 Molecule (CD68))
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Autre désignation
- CD68
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Sujet
- Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeablisation.Synonyms: Gp110, Macrophage marker, Macrosialin
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ID gène
- 12514
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NCBI Accession
- NP_033983
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UniProt
- P31996
Antigène
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