GM-CSF anticorps
Aperçu rapide pour GM-CSF anticorps (ABIN181873)
Antigène
Voir toutes GM-CSF (CSF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises recombinant and native GM-CSF. Clone 8D8 has been reported to neutralise the activity of both recombinant and native GM-CSF.
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Purification
- Affinity chromatography on Protein G
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Immunogène
- CHO expressed recombinant ovine GM-CSF. Spleen cells from immunised Balb/c mice were fused with cells of the NSO myeloma cell line.
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Isotype
- IgG1
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Indications d'application
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Western Blot. ELISA: 1/100 as detecting antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Autre désignation
- GM-CSF
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Sujet
- The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim
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ID gène
- 443400
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NCBI Accession
- NP_001009805
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UniProt
- P28773
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Pathways
- Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin
Antigène
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