MAP1LC3A anticorps (AA 2-15)

N° du produit ABIN1819535

L’anticorps Lapin Polyclonal anti-MAP1LC3A a été validé pour WB et IF. Il convient pour détecter MAP1LC3A dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Singe, Porc et Poisson.

Aperçu rapide pour MAP1LC3A anticorps (AA 2-15) (ABIN1819535)

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Singe, Porc, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1LC3A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MAP1LC3A anticorps

Épitope: AA 2-15

Specificité: Recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane. Recognizes both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B.

Purification: Affinity purified

Immunogène: Synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminal region of LC3A (NP_115903.1, NP_852610.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Pig, Opossum, Guinea pig, Salmon, Zebrafish (100%), Ferret, Dog, Cat, Lizard, Catfish, Stickleback, Medaka, Pufferfish (93%), Chicken, Pike (86%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IF, WB (1:100 - 1:250)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur MAP1LC3A

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Autre désignation: MAP1LC3A / LC3A

Sujet: Name/Gene ID: MAP1LC3A

Synonyms: MAP1LC3A, ATG8E, LC3, LC3A, MAP1BLC3, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3

ID gène: 84557

NCBI Accession: NP_115903, NP_852610

Pathways: Autophagy