TREM1 anticorps

N° du produit ABIN6796407

Cet anticorps anti-TREM1 est un anticorps Rat Monoclonal détectant TREM1 dans WB, FACS, IHC (fro) et IF. Adapté pour Souris.

Aperçu rapide pour TREM1 anticorps (ABIN6796407)

Antigène: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TREM1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: L5-B8-2A12-3A12

Détail du produit anti-TREM1 anticorps

Specificité: Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.

Purification: Protein G purified

Immunogène: Mouse TREM-1 Fc fusion protein.
Immunogen type: Fusion protein

Isotype: IgG2a

Information d'application

Indications d'application: Flo (1:25 - 1:100), IF, IHC-Fr, WB

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Détails sur TREM1

Antigène: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Autre désignation: TREM1 / TREM-1

Sujet: Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1

ID gène: 54210

UniProt: Q9NP99