VCAM1 anticorps (FITC)
Aperçu rapide pour VCAM1 anticorps (FITC) (ABIN1819980)
Antigène
Voir toutes VCAM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes rat CD106, otherwise known as VCAM-1 (vascular adhesion molecule 1), a 110kD inducible type I transmembrane glycoprotein and member of the immunoglobulin supergene family, which is predominantly expressed on vascular endothelium, and also on bone marrow stromal cells, follicular dendritic cells and some macrophages. CD106 interacts with the lymphocyte homing receptor VLA-4 (alpha4 beta1 integrin) and LPAM-1 (alpha4 beta7 integrin) and mediates leucocyte-endothelial cell adhesion and signal transduction. Expression of CD106 is upregulated following cytokine activation, and endothelial CD106 plays a role in the extravasation of leucocytes from blood vessels during inflammation.
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Purification
- Protein G purified
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Immunogène
- Rat CD106-transfected L5178Y cells.
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Isotype
- IgG1
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Indications d'application
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Approved: Flo (1:1 - 1:5), IF, IHC, IHC-Fr
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Protect from light.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Autre désignation
- VCAM1 / VCAM-1 / CD106
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Sujet
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Name/Gene ID: VCAM1
Family: ICAM
Synonyms: VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 -
ID gène
- 7412
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UniProt
- P19320
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Pathways
- Carbohydrate Homeostasis
Antigène
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