Lipoprotein Lipase anticorps (AA 380-410) (Biotin)

N° du produit ABIN1820142

Cet anticorps anti-Lipoprotein Lipase est un anticorps Souris Monoclonal détectant Lipoprotein Lipase dans WB, IP et ELISA. Adapté pour Humain, Rat, Boeuf (Vache), Porc, Poulet et Cobaye.

Aperçu rapide pour Lipoprotein Lipase anticorps (AA 380-410) (Biotin) (ABIN1820142)

Antigène: Lipoprotein Lipase (LPL)

Reactivité: Humain, Rat, Boeuf (Vache), Porc, Poulet, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lipoprotein Lipase est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Clone: 5D2

Détail du produit anti-Lipoprotein Lipase anticorps (Biotin)

Épitope: AA 380-410

Specificité: Recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues. A deficiency of LPL can result in hypertriglyceridemia, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Clone 5D2 has been shown to inhibit the activity of human LPL(2,3), and is widely used in human studies.

Aucune reactivité croisée: Souris

Purification: Protein G purified

Immunogène: Purified bovine milk lipoprotein lipase.

Type of Immunogen: Purified protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA (1:50 - 1:200), IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur Lipoprotein Lipase

Antigène: Lipoprotein Lipase (LPL)

Autre désignation: Lipoprotein Lipase / LPL

Sujet: Name/Gene ID: LPL

Synonyms: LPL, LIPD, Lipoprotein lipase, HDLCQ11

ID gène: 4023

UniProt: P06858

Pathways: Lipid Metabolism