IL-2 anticorps

N° du produit ABIN182113

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-2 dans WB et EIA. Il présente une réactivité avec des échantillons de Mouton.

Aperçu rapide pour IL-2 anticorps (ABIN182113)

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivité: Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-IL-2 anticorps

Specificité: Recognises ovine interleukin-2 (IL-2). No cross-reactivity is seen with ovine IL-1b, IL-6, IL-8, MCP-1 or TNF alpha.

Purification: None

Immunogène: Recombinant ovine IL-2

Information d'application

Indications d'application: Western blot. ELISA (1/500 detection, use ABIN119103 as coating antibody, It is recommended that ABIN182113 and any detection reagent are diluted in 10 % normal mouse serum prior to use in ELISA).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Serum stabilized by PBS and 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C or at -20 °C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: One year from despatch.

Date de péremption: 12 months

Détails sur IL-2

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Autre désignation: Interleukin-2 / IL2

Sujet: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

ID gène: 443401

UniProt: P19114

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation