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Aggrecan anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement Aggrecan dans WB, IHC, IP, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Boeuf (Vache).
N° du produit ABIN1834915

Aperçu rapide pour Aggrecan anticorps (ABIN1834915)

Antigène

Voir toutes Aggrecan (ACAN) Anticorps
Aggrecan (ACAN)

Reactivité

  • 83
  • 45
  • 31
  • 19
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Boeuf (Vache)

Hôte

  • 80
  • 22
  • 1
  • 1
Souris

Clonalité

  • 74
  • 30
Monoclonal

Conjugué

  • 52
  • 15
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Aggrecan est non-conjugé

Application

  • 74
  • 43
  • 27
  • 22
  • 19
  • 14
  • 14
  • 12
  • 8
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

7D4
  • Specificité

    Recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.

    Aucune reactivité croisée

    Poisson, Poulet, Rat (Rattus)

    Purification

    Protein G purified

    Immunogène

    Purified human articular cartilage aggrecan.

    Isotype

    IgG1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Antigène

    Aggrecan (ACAN)

    Autre désignation

    Aggrecan

    Sujet

    Name/Gene ID: ACAN

    Synonyms: ACAN, AGCAN, Aggrecan core protein, Acg1, Aggrecan, CSPG1, CSPGCP, CSPCP, AGC1, Aggrecan 1, Large aggregating proteoglycan, MSK16, SEDK, MCSPG

    ID gène

    176

    Pathways

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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