OLIG2 anticorps
Aperçu rapide pour OLIG2 anticorps (ABIN1845900)
Antigène
Voir toutes OLIG2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Immunogène
- Purified recombinant fragment of human OLIG2 expressed in E. coli.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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Autre désignation
- OLIG2
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Sujet
- This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain.The protein is an essential regulator of ventral neuroectodermal progenitor cell fate.The gene is involved in a chromosomal translocation t (14,21) (q11.2,q22) associated with T-cell acute lymphoblastic leukemia.Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.Tissue specificity: Expressed in the brain, in oligodendrocytes.Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas.Expression in glioblastomas highly variable.
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Poids moléculaire
- 32 kDa
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ID gène
- 10215, 50913, 304103
Antigène
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