Cadherin 5 anticorps (AA 29-223)
Aperçu rapide pour Cadherin 5 anticorps (AA 29-223) (ABIN1846316)
Antigène
Voir toutes Cadherin 5 (CDH5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 29-223
-
Purification
- Purified antibody
-
Immunogène
- Purified recombinant fragment of human CDH5 (AA: 29-223) expressed in E. coli.
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.0 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
-
-
- Cadherin 5 (CDH5)
-
Autre désignation
- CDH5
-
Sujet
- This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.An alternative splice variant has been described but its full length sequence has not been determined.
-
Poids moléculaire
- 87.5 kDa
-
ID gène
- 1003, 307618
-
Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Antigène
-