WHSC2 anticorps (AA 280-511)
Aperçu rapide pour WHSC2 anticorps (AA 280-511) (ABIN1846367)
Antigène
Voir toutes WHSC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 280-511
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. coli.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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Autre désignation
- WHSC2
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Sujet
- This gene is expressed ubiquitously with higher levels in fetal than in adult tissues.It encodes a protein sharing 93% sequence identity with the mouse protein.Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome.The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients.This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
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Poids moléculaire
- 57.3 kDa
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ID gène
- 7469
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Pathways
- Chromatin Binding
Antigène
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