IFT74 anticorps (C-Term)
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- Antigène Voir toutes IFT74 Anticorps
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IFT74 est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Fonction
- CMG1 / CCDC2 / IFT74
- Séquence
- KTIVDALHST SGN
- Réactivité croisée
- Humain, Rat
- Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Classe de qualité
- Verified
- Immunogène
- Peptide with sequence C-KTIVDALHSTSGN, from the C Terminus of the protein sequence according to NP_001092692.1, NP_001092693.1, NP_079379.2, AAK77221.1.
- Isotype
- IgG
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- Indications d'application
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Western Blot: Approx 70 kDa band observed in lysates of cell line HEK293 (calculated MW of 69.2 kDa according to AAK77221.1). The observed molecular weight corresponds to earlier findings in literature (Momeni et al, BMC Neurol. 2006 Dec 13,6:44., PMID: 17
Peptide ELISA: antibody detection limit dilution 1:32000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice." dans: The Journal of clinical investigation, Vol. 121, Issue 6, pp. 2169-80, (2011) (PubMed).
: "Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. ..." dans: BMC neurology, Vol. 6, pp. 44, (2007) (PubMed).
: "
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Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice." dans: The Journal of clinical investigation, Vol. 121, Issue 6, pp. 2169-80, (2011) (PubMed).
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- Antigène
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
- Autre désignation
- IFT74 (IFT74 Produits)
- Synonymes
- anticorps CCDC2, anticorps DKFZp469F1522, anticorps 1700029H06Rik, anticorps Ccdc2, anticorps Cmg1, anticorps b2b796Clo, anticorps CMG-1, anticorps CMG1, anticorps intraflagellar transport protein 74/72, anticorps intraflagellar transport 74, anticorps intraflagellar transport protein 74 homolog, anticorps IFT74, anticorps ift74, anticorps LOC100632007, anticorps LOC100649180, anticorps Ift74
- Sujet
- IFT74, CCDC2, CMG-1, FLJ22621, MGC111562, intraflagellar transport 74 homolog (Chlamydomonas), capillary morphogenesis protein 1, coiled-coil domain containing 2, CMG1
- ID gène
- 80173, 313365
- NCBI Accession
- NP_001092692, NP_001092693, NP_079379
- Pathways
- Signalisation Hedgehog, Chromatin Binding
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