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Aggrecan anticorps (AA 588-684)

L’anticorps Lapin Polyclonal anti-Aggrecan a été validé pour WB, IHC, IP et ICC. Il convient pour détecter Aggrecan dans des échantillons de Rat. Il y a 2+ publications disponibles.
N° du produit ABIN1857938

Aperçu rapide pour Aggrecan anticorps (AA 588-684) (ABIN1857938)

Antigène

Voir toutes Aggrecan (ACAN) Anticorps
Aggrecan (ACAN)

Reactivité

  • 84
  • 44
  • 31
  • 19
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Rat

Hôte

  • 79
  • 23
  • 1
  • 1
Lapin

Clonalité

  • 73
  • 31
Polyclonal

Conjugué

  • 52
  • 15
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Aggrecan est non-conjugé

Application

  • 74
  • 43
  • 27
  • 23
  • 18
  • 14
  • 14
  • 13
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • Épitope

    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 588-684

    Fonction

    Polyclonal Antibody to Aggrecan (AGC)

    Specificité

    The antibody is a rabbit polyclonal antibody raised against AGC. It has been selected for its ability to recognize AGC in immunohistochemical staining and western blotting.

     Réactivité croisée

    Humain

    Purification

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography

    Immunogène

    RPB908Ra02Recombinant Aggrecan (AGC)

    Isotype

    IgG
  • Indications d'application

    Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    Commentaires

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.3 mg/mL

    Buffer

    PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Chu, Dai, Wang, Tian, Song, Xiao, Shao, Zhang, Zhang: "Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis." dans: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 78, (2017) (PubMed).

    Dai, Chu, Tian, Song, Wang, Zhang, Zhang: "Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture in meniscectomized guinea pigs." dans: Osteoarthritis and cartilage, Vol. 24, Issue 6, pp. 1103-12, (2016) (PubMed).

  • Antigène

    Aggrecan (ACAN)

    Autre désignation

    Aggrecan

    Sujet

    ACAN, AGC1, AGCAN, CSPG1, CSPCP, CSPGCP, MSK16, SEDK, Cartilage-specific proteoglycan core protein, Large Aggregating Proteoglycan, Chondroitin Sulfate Proteoglycan 1

    Pathways

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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