BAFF anticorps

N° du produit ABIN187404

Cet anticorps anti-BAFF est un anticorps Rat Monoclonal détectant BAFF dans WB et FACS. Adapté pour Humain.

Aperçu rapide pour BAFF anticorps (ABIN187404)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: Buffy-1

Détail du produit anti-BAFF anticorps

Specificité: Recognizes the stalk region present in the membrane-bound form of human BAFF. Species Reactivity: Human, others not tested.

Immunogène: Human sol. BAFF (rec., aa. 83-285)

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: optimal concentration range is 0.5-5 µg/ml. Western blotting The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml. Purity > 95% as determined by SDS-PAGE. The antibody was purified from concentrated hybridoma cell culture supernatant.

Buffer: 100 µg in PBS and 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: CD257 / BAFF

Sujet: BAFF (for B-cell activating factor belonging to the TNF family), a new member of the tumor necrosis factor (TNF) family was simultaneously identified by four different laboratories and named BAFF, TALL-1, THANK, zTNF4. It is abundantly expressed in monocytes and macrophages, upregulated by interferon gamma. Endogenous BAFF is processed intracellularly by a protease of the furin family of proprotein convertases. Secreted BAFF acts as a potent B cell growth factor. Recently, two receptors for BAFF have been identified and termed as BCMA and TACI.

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response