ATG13 anticorps (pSer355)

N° du produit ABIN1881081

Cité dans 5 publications. Cet anticorps anti-ATG13 Polyclonal Lapin (Clone RB40774) (ABIN1881081) détecte spécifiquement ATG13 dans DB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ATG13 anticorps (pSer355) (ABIN1881081)

Antigène: ATG13 (Autophagy Related 13 (ATG13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG13 est non-conjugé

Application: Dot Blot (DB)

Clone: RB40774

Détail du produit anti-ATG13 anticorps

Épitope: pSer355

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ATG13 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S355 of human ATG13.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ATG13 (ABIN1881081)

Ferreira, Pan-Hammarström, Graham, Gateva, Fontán, Lee, Ortmann, Urcelay, Fernández-Arquero, Núñez, Jorgensen, Ludviksson, Koskinen, Haimila, Clark, Klareskog, Gregersen, Behrens, Hammarström: "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency." dans: Nature genetics, Vol. 42, Issue 9, pp. 777-80, (2010) (PubMed).

Koh, Lin, Jedd, Wong: "Sirius PSB: a generic system for analysis of biological sequences." dans: Journal of bioinformatics and computational biology, Vol. 7, Issue 6, pp. 973-90, (2009) (PubMed).

Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." dans: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." dans: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

Chan, Longatti, McKnight, Tooze: "Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism." dans: Molecular and cellular biology, Vol. 29, Issue 1, pp. 157-71, (2008) (PubMed).

Détails sur ATG13

Antigène: ATG13 (Autophagy Related 13 (ATG13))

Autre désignation: ATG13

Sujet: Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.

Poids moléculaire: 56572

NCBI Accession: NP_001136145, NP_001192048, NP_001192049, NP_001192050, NP_001192051, NP_055556

UniProt: O75143

Pathways: Signalisation PI3K-Akt, Autophagy