Cyclin B1 anticorps (pSer35)

N° du produit ABIN1881155

L’anticorps Lapin Polyclonal anti-Cyclin B1 a été validé pour WB et DB. Il convient pour détecter Cyclin B1 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour Cyclin B1 anticorps (pSer35) (ABIN1881155)

Antigène: Cyclin B1 (CCNB1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B1 est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB)

Clone: RB42141

Détail du produit anti-Cyclin B1 anticorps

Épitope: pSer35

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCNB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S35 of human CCNB1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1100. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Cyclin B1 (ABIN1881155)

Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: "Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." dans: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).

van Zon, Ogink, ter Riet, Medema, te Riele, Wolthuis: "The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit." dans: The Journal of cell biology, Vol. 190, Issue 4, pp. 587-602, (2010) (PubMed).

Harley, Allan, Sanderson, Clarke: "Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest." dans: The EMBO journal, Vol. 29, Issue 14, pp. 2407-20, (2010) (PubMed).

Détails sur Cyclin B1

Antigène: Cyclin B1 (CCNB1)

Autre désignation: CCNB1

Sujet: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

Poids moléculaire: 48337

NCBI Accession: NP_114172

UniProt: P14635

Pathways: Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase