Cyclin B2 anticorps (pSer22)

N° du produit ABIN1881157

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin B2 dans DB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 5+ publications.

Aperçu rapide pour Cyclin B2 anticorps (pSer22) (ABIN1881157)

Antigène: Cyclin B2 (CCNB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B2 est non-conjugé

Application: Dot Blot (DB)

Clone: RB42147

Détail du produit anti-Cyclin B2 anticorps

Épitope: pSer22

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S22 of human CCNB2.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Cyclin B2 (ABIN1881157)

Haraguchi, Ishikawa, Yamaguchi, Fujisawa: "Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." dans: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).

De Martino, Visone, Wierinckx, Palmieri, Ferraro, Cappabianca, Chiappetta, Forzati, Lombardi, Colao, Trouillas, Fedele, Fusco: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." dans: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).

Cunningham, Vierkant, Sellers, Phelan, Rider, Liebow, Schildkraut, Berchuck, Couch, Wang, Fridley, Gentry-Maharaj, Menon, Hogdall, Kjaer, Whittemore, DiCioccio, Song, Gayther, Ramus, Pharaoh, Goode: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." dans: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).

Bellanger, de Gramont, Sobczak-Thépot: "Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2." dans: Oncogene, Vol. 26, Issue 51, pp. 7175-84, (2007) (PubMed).

Stav, Bar, Sandbank: "Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma." dans: The International journal of biological markers, Vol. 22, Issue 2, pp. 108-13, (2007) (PubMed).

Détails sur Cyclin B2

Antigène: Cyclin B2 (CCNB2)

Autre désignation: CCNB2

Sujet: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

Poids moléculaire: 45282

NCBI Accession: NP_004692

UniProt: O95067

Pathways: Cycle Cellulaire, M Phase