Cyclin B3 anticorps (pThr280)

N° du produit ABIN1881173

3+ publications sont disponibles pour ce produit. L’anticorps anti-Cyclin B3 Polyclonal produit chez le Lapin a été validé pour DB. Il convient pour la détection de Cyclin B3 dans des échantillons provenant de Humain. }

Aperçu rapide pour Cyclin B3 anticorps (pThr280) (ABIN1881173)

Antigène: Cyclin B3 (CCNB3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B3 est non-conjugé

Application: Dot Blot (DB)

Clone: RB42155

Détail du produit anti-Cyclin B3 anticorps

Épitope: pThr280

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Cyclin B3 (ABIN1881173)

Cheng, Kapranov, Drenkow, Dike, Brubaker, Patel, Long, Stern, Tammana, Helt, Sementchenko, Piccolboni, Bekiranov, Bailey, Ganesh, Ghosh, Bell, Gerhard, Gingeras: "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." dans: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, (2005) (PubMed).

Mouland, Coady, Yao, Cohen: "Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression." dans: Virology, Vol. 292, Issue 2, pp. 321-30, (2002) (PubMed).

Nguyen, Manova, Capodieci, Lindon, Bottega, Wang, Refik-Rogers, Pines, Wolgemuth, Koff: "Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin." dans: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41960-9, (2002) (PubMed).

Détails sur Cyclin B3

Antigène: Cyclin B3 (CCNB3)

Autre désignation: CCNB3

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 157916

NCBI Accession: NP_149020, NP_391990

UniProt: Q8WWL7

Pathways: Cycle Cellulaire, Chromatin Binding