CTNS anticorps (C-Term)

N° du produit ABIN1881240

Détail du produit anti-CTNS anticorps

Antigène: CTNS (Cystinosis, Nephropathic (CTNS))

Épitope: AA 341-367, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNS est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the C-terminal region of human CTNS.

Clone: RB40519

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CTNS (ABIN1881240)

Taranta, Wilmer, van den Heuvel, Bencivenga, Bellomo, Levtchenko, Emma: "Analysis of CTNS gene transcripts in nephropathic cystinosis." dans: Pediatric nephrology (Berlin, Germany), Vol. 25, Issue 7, pp. 1263-7, (2010) (PubMed).

Kumar, Bachhawat: "A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis?" dans: Journal of biosciences, Vol. 35, Issue 1, pp. 21-5, (2010) (PubMed).

Bellomo, Corallini, Pastore, Palma, Laurenzi, Emma, Taranta: "Modulation of CTNS gene expression by intracellular thiols." dans: Free radical biology & medicine, Vol. 48, Issue 7, pp. 865-72, (2010) (PubMed).

Aldahmesh, Humeidan, Almojalli, Khan, Rajab, AL-Abbad, Meyer, Alkuraya: "Characterization of CTNS mutations in Arab patients with cystinosis." dans: Ophthalmic genetics, Vol. 30, Issue 4, pp. 185-9, (2009) (PubMed).

Macías-Vidal, Rodés, Hernández-Pérez, Vilaseca, Coll: "Analysis of the CTNS gene in 32 cystinosis patients from Spain." dans: Clinical genetics, Vol. 76, Issue 5, pp. 486-9, (2009) (PubMed).

Détails sur CTNS

Antigène: CTNS (Cystinosis, Nephropathic (CTNS))

Autre désignation: CTNS (CTNS Produits)

Synonymes: anticorps CTNS-LSB, anticorps PQLC4, anticorps AI195360, anticorps AW049661, anticorps zgc:110194, anticorps CTNS, anticorps cystinosin, lysosomal cystine transporter, anticorps cystinosis, nephropathic, anticorps cystinosin, lysosomal cystine transporter L homeolog, anticorps CTNS, anticorps Ctns, anticorps ctns, anticorps ctns.L

Sujet: This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 41738

NCBI Accession: NP_001026851, NP_004928

UniProt: O60931