Il existe 3+ publications pour ce produit.
L’anticorps anti-DDX19B Polyclonal Lapin est utilisé pour la détection de DDX19B dans des échantillons de Humain. Il a été validé pour WB.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This DDX19B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human DDX19B.
DDX19B
Reactivité: Humain
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Collins, Karlberg, Lehtiö, Schütz, van den Berg, Dahlgren, Hammarström, Weigelt, Schüler: "The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch." dans: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10296-300, (2009) (PubMed).
von Moeller, Basquin, Conti: "The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner." dans: Nature structural & molecular biology, Vol. 16, Issue 3, pp. 247-54, (2009) (PubMed).
Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." dans: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.