EPC1 anticorps (AA 305-334)

N° du produit ABIN1881300

Cet anticorps anti-EPC1 est un anticorps Lapin Polyclonal détectant EPC1 dans WB. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour EPC1 anticorps (AA 305-334) (ABIN1881300)

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EPC1 anticorps

Épitope: AA 305-334

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-EPC1 (ABIN1881300)

Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." dans: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).

Shimono, Murakami, Hasegawa, Takahashi: "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions." dans: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39411-9, (2001) (PubMed).

Détails sur EPC1

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Autre désignation: EPC1

Sujet: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Poids moléculaire: 93463

NCBI Accession: NP_001258933, NP_001258948, NP_001269320, NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation