Frataxin anticorps (N-Term)
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- Antigène Voir toutes Frataxin (FXN) Anticorps
- Frataxin (FXN)
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Épitope
- AA 36-64, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Frataxin est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
- Clone
- RB41914
- Isotype
- Ig Fraction
- Top Product
- Discover our top product FXN Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." dans: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).
: "The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals." dans: The Biochemical journal, Vol. 432, Issue 1, pp. 165-72, (2010) (PubMed).
: "Low predisposition to instability of the Friedreich ataxia gene in Cuban population." dans: Clinical genetics, Vol. 77, Issue 6, pp. 598-600, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
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Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." dans: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).
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- Antigène
- Frataxin (FXN)
- Autre désignation
- FXN (FXN Produits)
- Synonymes
- anticorps zgc:158218, anticorps LOC100284365, anticorps BcDNA:AT09528, anticorps CG8971, anticorps DFH, anticorps Dfh, anticorps Dmel\\CG8971, anticorps X25, anticorps dfh, anticorps CyaY, anticorps FA, anticorps FARR, anticorps FRDA, anticorps RGD1565754, anticorps Frda, anticorps frataxin, anticorps fxn, anticorps LOC100284365, anticorps TVAG_182150, anticorps fh, anticorps FTX1, anticorps FXN, anticorps Fxn
- Sujet
- This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 23135
- NCBI Accession
- NP_000135, NP_001155178, NP_852090
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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