GEMIN4 anticorps (N-Term)

N° du produit ABIN1881369

Cité dans 4 publications. Cet anticorps anti-GEMIN4 Polyclonal Lapin (Clone RB41821) (ABIN1881369) détecte spécifiquement GEMIN4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GEMIN4 anticorps (N-Term) (ABIN1881369)

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN4 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41821

Détail du produit anti-GEMIN4 anticorps

Épitope: AA 273-301, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GEMIN4 (ABIN1881369)

Clague, Lippman, Yang, Hildebrandt, Ye, Lee, Wu: "Genetic variation in MicroRNA genes and risk of oral premalignant lesions." dans: Molecular carcinogenesis, Vol. 49, Issue 2, pp. 183-9, (2010) (PubMed).

Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: "Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study." dans: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 913-21, (2010) (PubMed).

Wilker, Baccarelli, Suh, Vokonas, Wright, Schwartz: "Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes." dans: Environmental health perspectives, Vol. 118, Issue 7, pp. 943-8, (2010) (PubMed).

Ye, Wang, Gu, Yang, Lin, Ajani, Wu: "Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 1, Issue 6, pp. 460-9, (2009) (PubMed).

Détails sur GEMIN4

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Autre désignation: GEMIN4

Sujet: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Poids moléculaire: 120037

NCBI Accession: NP_056536

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization