GEMIN4 anticorps (AA 741-848)

N° du produit ABIN7153757

Détail du produit anti-GEMIN4 anticorps

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Épitope: AA 741-848

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Gem-associated protein 4 protein (741-848AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GEMIN4

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Autre désignation: GEMIN4 (GEMIN4 Produits)

Synonymes: anticorps HC56, anticorps HCAP1, anticorps HHRF-1, anticorps p97, anticorps 4932415L08Rik, anticorps AU015359, anticorps im:7143815, anticorps wu:fc41c09, anticorps zgc:110169, anticorps GEMIN4, anticorps RGD1563715, anticorps gem nuclear organelle associated protein 4, anticorps gem (nuclear organelle) associated protein 4, anticorps GEMIN4, anticorps Gemin4, anticorps gemin4

Sujet:

Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Aliases: GEMIN4 antibody, Gem-associated protein 4 antibody, Gemin-4 antibody, Component of gems 4 antibody, p97 antibody

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization