KISS1R anticorps (AA 235-263)

N° du produit ABIN1881480

Cet anticorps anti-KISS1R est un anticorps Lapin Polyclonal détectant KISS1R dans WB. Adapté pour Humain.

Aperçu rapide pour KISS1R anticorps (AA 235-263) (ABIN1881480)

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1R est non-conjugé

Application: Western Blotting (WB)

Clone: RB40407

Détail du produit anti-KISS1R anticorps

Épitope: AA 235-263

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur KISS1R

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Autre désignation: KISS1R

Sujet: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Poids moléculaire: 42586

NCBI Accession: NP_115940

UniProt: Q969F8