KRT6A anticorps (AA 212-240)

N° du produit ABIN1881486

Cité dans 5 publications. Cet anticorps anti-KRT6A Polyclonal Lapin (Clone RB40714) (ABIN1881486) détecte spécifiquement KRT6A dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour KRT6A anticorps (AA 212-240) (ABIN1881486)

Antigène: KRT6A (Keratin 6A (KRT6A))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Western Blotting (WB)

Clone: RB40714

Détail du produit anti-KRT6A anticorps

Épitope: AA 212-240

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-KRT6A (ABIN1881486)

Sehic, Khuu, Risnes, Osmundsen et al.: "Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of..." dans: European journal of oral sciences, Vol. 117, Issue 2, pp. 93-104, (2009) (PubMed).

Chen, Jaeger, Den, Koch, Sundberg, Roop: "Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita." dans: The Journal of investigative dermatology, Vol. 128, Issue 2, pp. 270-9, (2008) (PubMed).

Cui, Kunisada, Esibizione, Grivennikov, Piao, Nedospasov, Schlessinger: "Lymphotoxin-beta regulates periderm differentiation during embryonic skin development." dans: Human molecular genetics, Vol. 16, Issue 21, pp. 2583-90, (2007) (PubMed).

Gu, Coulombe: "Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles." dans: The Journal of investigative dermatology, Vol. 127, Issue 5, pp. 1061-73, (2007) (PubMed).

Kurek, Garinis, van Doorninck, van der Wees, Grosveld: "Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles." dans: Development (Cambridge, England), Vol. 134, Issue 2, pp. 261-72, (2006) (PubMed).

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: Krt6a

Sujet: Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77 % of all forms found in epithelia.

Poids moléculaire: 59335

NCBI Accession: NP_032502

UniProt: P50446