MAVS anticorps (N-Term)

N° du produit ABIN1881530

Il existe 1 publication pour ce produit. L’anticorps anti-MAVS Polyclonal Lapin est utilisé pour la détection de MAVS dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour MAVS anticorps (N-Term) (ABIN1881530)

Antigène: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAVS est non-conjugé

Application: Western Blotting (WB)

Clone: RB42373

Détail du produit anti-MAVS anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MAVS (ABIN1881530)

Ichinohe, Pang, Iwasaki: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." dans: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).

Détails sur MAVS

Antigène: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Autre désignation: Mavs

Sujet: Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).

Poids moléculaire: 53399

NCBI Accession: NP_001193314, NP_659137

UniProt: Q8VCF0

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C