MAVS anticorps (AA 1-65)
Aperçu rapide pour MAVS anticorps (AA 1-65) (ABIN6143583)
Antigène
Voir toutes MAVS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-65
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Séquence
- MPFAEDKTYK YICRNFSNFC NVDVVEILPY LPCLTARDQD RLRATCTLSG NRDTLWHLFN TLQRR
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-65 of human MAVS (NP_065797.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." dans: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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Autre désignation
- MAVS
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Sujet
- This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene.,CARDIF,IPS-1,IPS1,VISA,MAVS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,MAVS
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Poids moléculaire
- 14 kDa/15 kDa/17 kDa/40 kDa/56 kDa
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ID gène
- 57506
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UniProt
- Q7Z434
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Pathways
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
Antigène
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