MTHFR anticorps (AA 266-292)

N° du produit ABIN1881559

Cet anticorps Lapin Polyclonal détecte spécifiquement MTHFR dans WB. Il présente une réactivité envers Humain et a été mentionné dans 5+ publications.

Aperçu rapide pour MTHFR anticorps (AA 266-292) (ABIN1881559)

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTHFR est non-conjugé

Application: Western Blotting (WB)

Clone: RB41196

Détail du produit anti-MTHFR anticorps

Épitope: AA 266-292

Homologie: B, Pr, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MTHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MTHFR (ABIN1881559)

Singh, Singh, Raman: "MTHFR A1298C polymorphism and idiopathic male infertility." dans: Journal of postgraduate medicine, Vol. 56, Issue 4, pp. 267-9, (2010) (PubMed).

Harisha, Devi, Christopher, Kruthika-Vinod: "Impact of 5,10-methylenetetrahydrofolate reductase gene polymorphism on neural tube defects." dans: Journal of neurosurgery. Pediatrics, Vol. 6, Issue 4, pp. 364-7, (2010) (PubMed).

Wu, Chang, Tsai, Lin, Wang, Tsai, Chen, Yao, Chiu, Bau, Lin: "Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan." dans: Anticancer research, Vol. 30, Issue 9, pp. 3573-7, (2010) (PubMed).

Magnowski, Seremak-Mrozikiewicz, Nowak-Markwitz, Kurzawińska, Drews, Spaczyński: "[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region]." dans: Ginekologia polska, Vol. 81, Issue 7, pp. 506-10, (2010) (PubMed).

Kristensen, Pedersen, Melsen, Ellehauge, Mejer: "Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients." dans: The Journal of international medical research, Vol. 38, Issue 3, pp. 870-83, (2010) (PubMed).

Détails sur MTHFR

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Autre désignation: MTHFR

Sujet: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Poids moléculaire: 74597

NCBI Accession: NP_005948

UniProt: P42898

Pathways: Methionine Biosynthetic Process