POLK anticorps (AA 531-560)
Aperçu rapide pour POLK anticorps (AA 531-560) (ABIN1881669)
Antigène
Voir toutes POLK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 531-560
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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Autre désignation
- POLK
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Sujet
- External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).
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Poids moléculaire
- 98809
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NCBI Accession
- NP_057302
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UniProt
- Q9UBT6
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Pathways
- Réparation de l'ADN
Antigène
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