POLK anticorps (AA 531-560)

N° du produit ABIN1881669

Détail du produit anti-POLK anticorps

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Épitope: AA 531-560

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLK est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK.

Clone: RB41936

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur POLK

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Autre désignation: POLK (POLK Produits)

Synonymes: anticorps DINB1, anticorps DINP, anticorps POLQ, anticorps Dinb1, anticorps POLK, anticorps si:ch211-254o18.3, anticorps DNA polymerase kappa, anticorps polymerase (DNA directed) kappa, anticorps polymerase (DNA directed), kappa, anticorps polymerase (DNA directed) kappa L homeolog, anticorps POLK, anticorps Polk, anticorps polk, anticorps Tb11.01.0080, anticorps Tb11.01.0010, anticorps Tb11.01.0020, anticorps Tb11.01.0030, anticorps Tb11.01.0040, anticorps Tb11.01.0050, anticorps Tb11.12.0001, anticorps Tb11.12.0002, anticorps Tb11.12.0003, anticorps polk.L, anticorps polk-1

Sujet: External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).

Poids moléculaire: 98809

NCBI Accession: NP_057302

UniProt: Q9UBT6

Pathways: Réparation de l'ADN