PSPH anticorps (N-Term)

N° du produit ABIN1881701

Il existe 3+ publications pour ce produit. L’anticorps anti-PSPH Polyclonal Lapin est utilisé pour la détection de PSPH dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour PSPH anticorps (N-Term) (ABIN1881701)

Antigène: PSPH (Phosphoserine Phosphatase (PSPH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSPH est non-conjugé

Application: Western Blotting (WB)

Clone: RB42215

Détail du produit anti-PSPH anticorps

Épitope: AA 7-36, N-Term

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PSPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human PSPH.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:8000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PSPH (ABIN1881701)

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." dans: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Veiga-da-Cunha, Collet, Prieur, Jaeken, Peeraer, Rabbijns, Van Schaftingen: "Mutations responsible for 3-phosphoserine phosphatase deficiency." dans: European journal of human genetics : EJHG, Vol. 12, Issue 2, pp. 163-6, (2004) (PubMed).

Peeraer, Rabijns, Verboven, Collet, Van Schaftingen, De Ranter: "High-resolution structure of human phosphoserine phosphatase in open conformation." dans: Acta crystallographica. Section D, Biological crystallography, Vol. 59, Issue Pt 6, pp. 971-7, (2003) (PubMed).

Détails sur PSPH

Antigène: PSPH (Phosphoserine Phosphatase (PSPH))

Autre désignation: PSPH

Sujet: The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.

Poids moléculaire: 25008

NCBI Accession: NP_004568

UniProt: P78330

Pathways: L'effet Warburg