Poliovirus Receptor anticorps (C-Term)

N° du produit ABIN1881709

Cet anticorps Lapin Polyclonal détecte spécifiquement Poliovirus Receptor dans WB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.

Aperçu rapide pour Poliovirus Receptor anticorps (C-Term) (ABIN1881709)

Antigène: Poliovirus Receptor (PVR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Poliovirus Receptor est non-conjugé

Application: Western Blotting (WB)

Clone: RB41981

Détail du produit anti-Poliovirus Receptor anticorps

Épitope: AA 314-342, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Poliovirus Receptor (ABIN1881709)

Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: "Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma." dans: Cancer science, Vol. 101, Issue 5, pp. 1326-30, (2010) (PubMed).

Carlsten, Norell, Bryceson, Poschke, Schedvins, Ljunggren, Kiessling, Malmberg: "Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 8, pp. 4921-30, (2009) (PubMed).

Kindberg, Ax, Fiore, Svensson: "Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis." dans: Journal of medical virology, Vol. 81, Issue 5, pp. 933-6, (2009) (PubMed).

Détails sur Poliovirus Receptor

Antigène: Poliovirus Receptor (PVR)

Autre désignation: PVR

Sujet: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 45303

NCBI Accession: NP_001129240, NP_001129241, NP_001129242, NP_006496

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome