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RAB27A anticorps (C-Term)

Cet anticorps anti-RAB27A est un anticorps Lapin Polyclonal détectant RAB27A dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 5+ publications.
N° du produit ABIN1881720

Aperçu rapide pour RAB27A anticorps (C-Term) (ABIN1881720)

Antigène

Voir toutes RAB27A Anticorps
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reactivité

  • 50
  • 23
  • 21
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 37
  • 10
  • 3
  • 2
Lapin

Clonalité

  • 40
  • 12
Polyclonal

Conjugué

  • 31
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp RAB27A est non-conjugé

Application

  • 36
  • 23
  • 14
  • 11
  • 10
  • 6
  • 5
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB42745
  • Épitope

    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 136-164, C-Term

    Homologie

    M, Pig, Rat

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: "Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2." dans: Pigment cell & melanoma research, Vol. 23, Issue 3, pp. 365-74, (2010) (PubMed).

    Meeths, Bryceson, Rudd, Zheng, Wood, Ramme, Beutel, Hasle, Heilmann, Hultenby, Ljunggren, Fadeel, Nordenskjöld, Henter: "Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations." dans: Pediatric blood & cancer, Vol. 54, Issue 4, pp. 563-72, (2010) (PubMed).

    Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

    Chattopadhyay, Singh, Phukan, Purkayastha, Kataki, Mahanta, Saxena, Kapur: "Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India." dans: Mutation research, Vol. 696, Issue 2, pp. 130-8, (2010) (PubMed).

    Wood, Meeths, Chiang, Bechensteen, Boelens, Heilmann, Horiuchi, Rosthøj, Rutynowska, Winiarski, Stow, Nordenskjöld, Henter, Ljunggren, Bryceson: "Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity." dans: Blood, Vol. 114, Issue 19, pp. 4117-27, (2009) (PubMed).

  • Antigène

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    Autre désignation

    RAB27A

    Sujet

    The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

    Poids moléculaire

    24868

    NCBI Accession

    NP_004571, NP_899057, NP_899058, NP_899059

    UniProt

    P51159

    Pathways

    Peptide Hormone Metabolism
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