RGS2 anticorps (N-Term)

N° du produit ABIN1881749

L’anticorps Lapin Polyclonal anti-RGS2 a été validé pour WB. Il convient pour détecter RGS2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour RGS2 anticorps (N-Term) (ABIN1881749)

Antigène: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41808

Détail du produit anti-RGS2 anticorps

Épitope: AA 4-32, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human RGS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-RGS2 (ABIN1881749)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Wang, Lippman, Lee, Yang, Khuri, Kim, Lin, Chang, Lotan, Hong, Wu: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." dans: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).

Détails sur RGS2

Antigène: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Autre désignation: RGS2

Sujet: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

Poids moléculaire: 24382

NCBI Accession: NP_002914

UniProt: P41220

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation