TIAM1 anticorps (C-Term)

N° du produit ABIN1881884

Il existe 3+ publications pour ce produit. L’anticorps anti-TIAM1 Polyclonal Lapin est utilisé pour la détection de TIAM1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour TIAM1 anticorps (C-Term) (ABIN1881884)

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAM1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41848

Détail du produit anti-TIAM1 anticorps

Épitope: AA 1478-1506, C-Term

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-TIAM1 (ABIN1881884)

Yang, Lv, Liu, Liu, Yang, Hu: "Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma." dans: Japanese journal of clinical oncology, Vol. 40, Issue 11, pp. 1053-9, (2010) (PubMed).

Moriarty, Pursell, Mercurio: "miR-10b targets Tiam1: implications for Rac activation and carcinoma migration." dans: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20541-6, (2010) (PubMed).

Shepherd, Klaus, Liu, Ramaswamy, DeMali, Fuentes: "The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion." dans: Journal of molecular biology, Vol. 398, Issue 5, pp. 730-46, (2010) (PubMed).

Détails sur TIAM1

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Autre désignation: TIAM1

Sujet: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.

Poids moléculaire: 177508

NCBI Accession: NP_003244

UniProt: Q13009