TSC1 anticorps (pThr416)

N° du produit ABIN1881922

Cet anticorps Lapin Polyclonal détecte spécifiquement TSC1 dans DB. Il présente une réactivité envers Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour TSC1 anticorps (pThr416) (ABIN1881922)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Dot Blot (DB)

Clone: RB42189

Détail du produit anti-TSC1 anticorps

Épitope: pThr416

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T416 of mouse TSC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-TSC1 (ABIN1881922)

Akpa, Oyejola: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." dans: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).

Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." dans: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Poids moléculaire: 128746

NCBI Accession: NP_075025

UniProt: Q9EP53

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation