TSC1 anticorps (C-Term)

N° du produit ABIN1881923

L’anticorps Lapin Polyclonal anti-TSC1 a été validé pour WB. Il convient pour détecter TSC1 dans des échantillons de Souris.

Aperçu rapide pour TSC1 anticorps (C-Term) (ABIN1881923)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42188

Détail du produit anti-TSC1 anticorps

Épitope: AA 1117-1144, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1144 amino acids from the C-terminal region of mouse TSC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Poids moléculaire: 128746

NCBI Accession: NP_075025

UniProt: Q9EP53

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation