TSC1 anticorps (AA 395-424)

N° du produit ABIN1881924

Cet anticorps anti-TSC1 est un anticorps Lapin Polyclonal détectant TSC1 dans WB. Adapté pour Humain.

Aperçu rapide pour TSC1 anticorps (AA 395-424) (ABIN1881924)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42204

Détail du produit anti-TSC1 anticorps

Épitope: AA 395-424

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Poids moléculaire: 129767

NCBI Accession: NP_000359, NP_001155898, NP_001155899

UniProt: Q92574

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation