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TSC1 anticorps (pThr310)

TSC1 Reactivité: Humain DB Hôte: Lapin Polyclonal RB42049 unconjugated
N° du produit ABIN1881928
  • Antigène Voir toutes TSC1 Anticorps
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Épitope
    • 24
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr310
    Reactivité
    • 187
    • 139
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 301
    • 16
    • 1
    • 1
    Lapin
    Clonalité
    • 303
    • 16
    Polyclonal
    Conjugué
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp TSC1 est non-conjugé
    Application
    • 230
    • 207
    • 92
    • 28
    • 26
    • 26
    • 16
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T310 of human TSC1.
    Clone
    RB42049
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TSC1 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." dans: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, (2011) (PubMed).

    Hoogeveen-Westerveld, Exalto, Maat-Kievit, van den Ouweland, Halley, Nellist: "Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction." dans: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 774-81, (2010) (PubMed).

    Mieulet, Lamb: "Tuberous sclerosis complex: linking cancer to metabolism." dans: Trends in molecular medicine, Vol. 16, Issue 7, pp. 329-35, (2010) (PubMed).

    Guo, Ying, Zhang, Yuan, Qian, Wang, Yang, He: "Tandem affinity purification and identification of the human TSC1 protein complex." dans: Acta biochimica et biophysica Sinica, Vol. 42, Issue 4, pp. 266-73, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • Antigène
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Autre désignation
    TSC1 (TSC1 Produits)
    Synonymes
    anticorps LAM, anticorps TSC, anticorps hamartin, anticorps mKIAA0243, anticorps tsc1, anticorps wu:fc38b04, anticorps fa99f04, anticorps wu:fa99f04, anticorps zgc:63657, anticorps TSC complex subunit 1, anticorps tuberous sclerosis 1, anticorps TSC complex subunit 1b, anticorps TSC complex subunit 1a, anticorps TSC1, anticorps Tsc1, anticorps tsc1b, anticorps tsc1, anticorps tsc1a
    Sujet
    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    129767
    NCBI Accession
    NP_000359, NP_001155898, NP_001155899
    UniProt
    Q92574
    Pathways
    Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
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