UBE2S anticorps (C-Term)

N° du produit ABIN1881968

Il existe 5+ publications pour ce produit. L’anticorps anti-UBE2S Polyclonal Lapin est utilisé pour la détection de UBE2S dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour UBE2S anticorps (C-Term) (ABIN1881968)

Antigène: UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2S est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB42367

Détail du produit anti-UBE2S anticorps

Épitope: AA 183-210, C-Term

Homologie: X, B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UBE2S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-210 amino acids from the C-terminal region of human UBE2S.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-UBE2S (ABIN1881968)

Wu, Merbl, Huo, Gallop, Tzur, Kirschner: "UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1355-60, (2010) (PubMed).

Williamson, Wickliffe, Mellone, Song, Karpen, Rape: "Identification of a physiological E2 module for the human anaphase-promoting complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 43, pp. 18213-8, (2009) (PubMed).

Chen, Lee, Lu, Chen, Hsieh, Liu, Lin, Chen: "The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma." dans: Journal of molecular medicine (Berlin, Germany), Vol. 87, Issue 3, pp. 307-20, (2009) (PubMed).

Garnett, Mansfeld, Godwin, Matsusaka, Wu, Russell, Pines, Venkitaraman: "UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit." dans: Nature cell biology, Vol. 11, Issue 11, pp. 1363-9, (2009) (PubMed).

Lim, Jung, Lee, Im: "Egr-1 and serum response factor are involved in growth factors- and serum-mediated induction of E2-EPF UCP expression that regulates the VHL-HIF pathway." dans: Journal of cellular biochemistry, Vol. 105, Issue 4, pp. 1117-27, (2008) (PubMed).

Détails sur UBE2S

Antigène: UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

Autre désignation: UBE2S

Sujet: This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.

Poids moléculaire: 23845

NCBI Accession: NP_055316

UniProt: Q16763

Pathways: Ubiquitin Proteasome Pathway