PA2G4 anticorps (C-Term)

N° du produit ABIN1882075

Cet anticorps Lapin Polyclonal détecte spécifiquement PA2G4 dans WB, FACS et IHC (p). Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour PA2G4 anticorps (C-Term) (ABIN1882075)

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PA2G4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19220

Détail du produit anti-PA2G4 anticorps

Épitope: AA 322-350, C-Term

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human EBP1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PA2G4 (ABIN1882075)

Zhang, Linn, Liu, Melamed, Tavora, Young, Burger, Hamburger: "EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance." dans: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3176-86, (2008) (PubMed).

Détails sur PA2G4

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Autre désignation: EBP1

Sujet: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.

Poids moléculaire: 43787

NCBI Accession: NP_006182

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades