FDPS anticorps (N-Term)

N° du produit ABIN1882080

Détail du produit anti-FDPS anticorps

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Épitope: AA 82-112, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the N-terminal region of human FDPS.

Clone: RB4783-4784

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:100. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-FDPS (ABIN1882080)

Wilkin, Kutsunai, Edwards et al.: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." dans: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).

Sheares, White, Molowa, Chan, Ding, Kroon, Bostedor, Karkas: "Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells." dans: Biochemistry, Vol. 28, Issue 20, pp. 8129-35, (1990) (PubMed).

Détails sur FDPS

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Autre désignation: FDPS (FDPS Produits)

Synonymes: anticorps CG12389, anticorps DmFPPS, anticorps DmFPPSase, anticorps DmFPS, anticorps Dmel\\CG12389, anticorps FPS, anticorps fpps, anticorps fps, anticorps l(2)k06103, anticorps v(2)k03514, anticorps NCU01175.1, anticorps 16.m00760, anticorps DDBDRAFT_0206220, anticorps DDBDRAFT_0215017, anticorps DDB_0206220, anticorps DDB_0215017, anticorps FPPS, anticorps Ac2-125, anticorps (2E, anticorps 6030492I17Rik, anticorps AI256750, anticorps Fdpsl1, anticorps mKIAA1293, anticorps Farnesyl pyrophosphate synthase, anticorps farnesyl diphosphate synthase, anticorps farnesyl diphosphate synthase L homeolog, anticorps farnesyl pyrophosphate synthase, anticorps farnesyl pyrophosphate synthetase, anticorps farnesyl-pyrophosphate synthetase, anticorps FDP synthase, anticorps Farnesyl pyrophosphate synthetase, anticorps farnesyl diphosphate synthetase, anticorps farnesyl pyrophosphate synthase 1, anticorps Fpps, anticorps fdps, anticorps fdps.L, anticorps MGG_08649, anticorps TP03_0857, anticorps Tb09.160.4300, anticorps fpp, anticorps BBOV_I000120, anticorps fps, anticorps fpps, anticorps FDPS, anticorps Fdps, anticorps fps1

Sujet: The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.

Poids moléculaire: 48275

NCBI Accession: NP_001129293, NP_001129294, NP_001229753, NP_001229754, NP_001995

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation