UBE2K anticorps (AA 109-139)
Aperçu rapide pour UBE2K anticorps (AA 109-139) (ABIN1882088)
Antigène
Voir toutes UBE2K AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 109-139
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Homologie
- B
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.
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Isotype
- Ig Fraction
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Indications d'application
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." dans: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).
: "Recent advances on the pathogenesis of Huntington's disease." dans: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).
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: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." dans: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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Autre désignation
- HIP2
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Sujet
- HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
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Poids moléculaire
- 22407
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NCBI Accession
- NP_001104582, NP_001104583, NP_005330
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UniProt
- P61086
Antigène
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